Article
Mucosal immunity and inflammation. I. Mucosal dendritic cells: their specialized role in initiating T cell responses.
The American journal of physiology - 1 May 1999
Iwasaki A, Kelsall B L
Abstract excerpt
Dendritic cells (DCs) are the most competent antigen-presenting cells known for the induction of primary T cell responses. Functional studies of tissue-resident DCs have been impaired by the rarity of these cells in any given organ. Recent development of isolation procedures allowing extraction of highly purified fresh DC populations has made it possible to study mucosal DCs in distinct mucosa-associated lymphoid...
Topics
- Animals
- Dendritic Cells
- Humans
- Inflammation
- Intestinal Mucosa
- Mucous Membrane
- Peyer's Patches
- Phenotype
- T-Lymphocytes
