Article
Novel lethal mouse mutants produced in balancer chromosome screens.
Gene expression patterns : GEP - 1 Aug 2006
Hentges Kathryn E, Nakamura Hisashi, Furuta Yasuhide, Yu Yuejin, Thompson Debrah M, O'Brien William, Bradley Allan, Justice Monica J
Abstract excerpt
Mutagenesis screens are a valuable method to identify genes that are required for normal development. Previous mouse mutagenesis screens for lethal mutations were targeted at specific time points or for developmental processes. Here we present the results of lethal mutant isolation from two mutagenesis screens that use balancer chromosomes. One screen was localized to mouse chromosome 4, between the STS markers...
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