Article
Strategies for Maintaining Mouse Mutations.
Cold Spring Harbor protocols - 2 Jan 2024
Papaioannou Virginia E, Behringer Richard R
Abstract excerpt
Rules for naming a new mutation are provided. The majority of new mutations are recessive and thus easily maintained in a mouse strain. Considerations on the choice of genetic background are given, depending on how the mutant was produced and how you intend to analyze it. General information on maintaining a mutant colony to perpetuate the mutation and to efficiently produce homozygous mutant mice for analysis is...
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