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Expression of the c-Met proto-oncogene and its possible involvement in liver invasion in adult T-cell leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2003

Imaizumi Yoshitaka, Murota Hiroyuki, Kanda Shigeru, Hishikawa Yoshitaka, Koji Takehiko, Taguchi Takashi, Tanaka Yuetsu, Yamada Yasuaki, Ikeda Shuichi, Kohno Tomoko, Yamamoto Kazuo, Mori Naoki, Tomonaga Masao, Matsuyama Toshifumi

Abstract excerpt

c-Met is a tyrosine kinase receptor for hepatocyte growth factor and suggested to be involved in oncogenesis ormetastatic phenotypes in many malignancies. Adult T-cell leukemia (ATL) is a neoplasia characterized by massive invasion of the leukemic cells into various organs. Recently, we have reported frequent hepatic involvement and the relationship between liver invasion and the poor prognosis in ATL. In the...

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PMID: 12538467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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