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Article

HLA-DP molecules bind cobalt: a possible explanation for the genetic association with hard metal disease.

European journal of immunology - 1 Jul 1999

Potolicchio I, Festucci A, Hausler P, Sorrentino R

Abstract excerpt

Metal dust inhalation induces an interstitial lung disease which may progress to pulmonary fibrosis (hard metal disease, HMD). Cobalt is believed to be the pathogenic agent of HMD. A strong genetic association of HMD with some HLA-DP alleles has been reported although the role of these molecules...

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Source

Identifiers

PMID: 10427976
DOI: 10.1002/(SICI)1521-4141(199907)29:07<2140::AID-IMMU2140>3.0.CO;2-Q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10427976-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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