Article
Expression of the 180-kD ribosome receptor induces membrane proliferation and increased secretory activity in yeast.
The Journal of cell biology - 26 Jul 1999
Becker F, Block-Alper L, Nakamura G, Harada J, Wittrup K D, Meyer D I
Abstract excerpt
Expression of the canine 180-kD ribosome receptor (p180) in yeast cells resulted in a marked proliferation of intracellular membranes. The type of membranes observed varied with the expression of specific portions of p180. Rough membranes predominated when the ribosome binding domain of p180 was present, whereas expression constructs lacking this region resulted in smooth membranes. Northern analysis indicated...
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