Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

P53 genotyping - an effective concept for molecular testing of head and neck cancer?

International journal of molecular medicine - 1 Sept 1999

Dahse R, Fiedler W, von Eggeling F, Schimmel B, Koscielny S, Beleites E, Claussen U, Ernst G

Abstract excerpt

P53 mutations are currently recognized as the most common genetic alteration in human tumors. The purpose of our study was to evaluate the significance and reliability of p53 genotyping in head and neck cancer as a possible marker permitting the prediction of tumor behavior and clinical outcome. P53 genotyping in our study refers to highly sensitive molecular screening in order to detect structural alterations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Fingerprinting

Share to Genes, p53

Share to Genotype

Share to Head and Neck Neoplasms

Share to Neoplasm Staging

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 10425279
DOI: 10.3892/ijmm.4.3.279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

P53 genotyping - an effective concept for molecular testing of head and neck cancer?PMID 10425279Read ↗

Head and neck tumor sites differ in prevalence and spectrum of <i>p53</i> alterations but these have limited prognostic valueSemantic proximity Read ↗

Evaluation of p53 protein as a prognostic factor for oral cancer surgery.Semantic proximity Read ↗

The incidence of p53 mutations increases with progression of head and neck cancer.Semantic proximity Read ↗

TP53 genetic alterations in head-and-neck carcinomas from Brazil.Semantic proximity Read ↗

Value of p53 sequencing in the prognostication of head and neck cancer: a systematic review and meta-analysisSemantic proximity Read ↗

[p53 mutations and HPV infections in squamous epithelial carcinomas of the head-neck region. Long-term follow-up].Semantic proximity Read ↗

The role of p53 tumor suppressor gene in human head and neck tumorigenesis.Semantic proximity Read ↗

Stage-independent expression and genetic analysis of tp73 in neuroblastoma.Semantic proximity Read ↗

Associations of TP53 mutations, codon 72 polymorphism and human papillomavirus in head and neck squamous cell carcinoma patients.Semantic proximity Read ↗

Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers.Semantic proximity Read ↗

p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutationsSemantic proximity Read ↗

p53 mutations in human head and neck cancer cell lines.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.