Article
Genetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenoma.
Molecular and cellular endocrinology - 5 Apr 2014
Zhou Yunli, Zhang Xun, Klibanski Anne
Abstract excerpt
Human pituitary adenomas are the most common intracranial neoplasms. Approximately 5% of them are familial adenomas. Patients with familial tumors carry germline mutations in predisposition genes, including AIP, MEN1 and PRKAR1A. These mutations are extremely rare in sporadic pituitary adenomas,...
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