Article
Electrophoretic analysis of oxidative modification of apolipoprotein E in very low density lipoprotein from fresh human plasma.
Electrophoresis - 1 Jun 1999
Kashiwagi S, Nakamura K, Arai H, Yamashita H, Ito H
Abstract excerpt
Ferrous ion-induced oxidative modification of apoE in lipid peroxidation of human very low density lipoprotein (VLDL) and the role of the cysteinyl group, present in apoE3 but absent in apoE4, were examined. Fresh human VLDL was obtained from healthy volunteers with different apoE phenotypes as determined by isoelectric focusing (IEF). The VLDL was oxidized by incubating with FeSO4. The time course of the lipid...
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