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Article

Differential oxidation of apolipoprotein E isoforms and interaction with phospholipids.

Free radical biology & medicine - 1 Jan 2000

Jolivalt C, Leininger-Muller B, Bertrand P, Herber R, Christen Y, Siest G

Abstract excerpt

Accumulation of oxidized proteins has been demonstrated in the brain of patients suffering from Alzheimer's disease (AD). Among the proteins found in cerebral amyloid deposits, apolipoprotein (apo) E is a polymorphic protein which one specific isoform, apo E4, has been widely associated with AD. Apo E may be linked with AD by its isoform-specific interaction with lipids or other proteins in amyloid plaques. Using...

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Identifiers

PMID: 10656299
DOI: 10.1016/s0891-5849(99)00232-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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