Article
Detection of specifically oxidized apolipoproteins in oxidized HDL.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Wang Xiao Suo, Stocker Roland
Abstract excerpt
Atherosclerosis is associated with dysfunctional HDL, and oxidation of HDL is thought to give rise to HDL becoming dysfunctional. Lipoprotein oxidation represents a complex series of processes that can be assessed by various methods. In general, oxidation mediated by 1-electron or radical oxidants gives rise to lipid hydroperoxides (LOOHs) as the primary product. These LOOHs may then undergo further reactions...
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