Article
Characterization of specifically oxidized apolipoproteins in mildly oxidized high density lipoprotein.
Journal of lipid research - 1 Feb 2003
Pankhurst Greg, Wang Xing Li, Wilcken David E, Baernthaler Georg, Panzenböck Ute, Raftery Mark, Stocker Roland
Abstract excerpt
Atherosclerosis is a state of heightened oxidative stress. Oxidized LDL is present in atherosclerotic lesions and used as marker for coronary artery disease, although in human lesions lipids associated with HDL are as oxidized as those of LDL. Here we investigated specific changes occurring to apolipoprotein A-I (apoA-I) and apoA-II, as isolated HDL and human plasma undergo mild, chemically induced oxidation, or...
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