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Article

Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesis.

PloS one - 11 Nov 2009

Nemajerova Alice, Palacios Gustavo, Nowak Norma J, Matsui Sei-Ichi, Petrenko Oleksi

Abstract excerpt

Transcriptional silencing of the p73 gene through methylation has been demonstrated in human leukemias and lymphomas. However, the role of p73 in the malignant process remains to be explored. We show here that p73 acts as a T cell-specific tumor suppressor in a genetically defined mouse model, an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19907659
DOI: 10.1371/journal.pone.0007784
PMCID: PMC2771421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19907659-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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