Article
Prognostic significance of bcl-2 expression in leiomyosarcoma of the uterus.
British journal of cancer - 1 Jul 1999
Zhai Y L, Nikaido T, Toki T, Shiozawa A, Orii A, Fujii S
Abstract excerpt
We examined bcl-2 expression as well as p53 expression and mutation in human uterine smooth muscle tumours to determine the influence of bcl-2 expression on prognosis in patients with uterine leiomyosarcomas. bcl-2 protein was expressed in nearly all benign smooth muscle tumours but in only 57% of leiomyosarcomas. Benign smooth muscle tumours were usually negative for p53 protein, but 16 out of 21 (76%)...
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