Article
The human alpha subunit glycoprotein hormone gene utilizes a unique CCAAT binding factor.
The Journal of biological chemistry - 15 Apr 1990
Kennedy G C, Andersen B, Nilson J H
Abstract excerpt
Placenta-specific expression of the gene encoding the alpha subunit of glycoprotein hormones involves the interaction of at least two different cis-acting elements: the upstream regulatory element (URE), which binds a placenta-specific trans-acting factor; and two tandem cAMP-response elements (CREs), which bind a ubiquitous protein (CRE-binding protein). To identify additional elements required for promoter...
Topics
- Base Sequence
- Cell Line
- Cell Nucleus
- Choriocarcinoma
- DNA Probes
- DNA-Binding Proteins
- Female
- Genes
- Genes, Regulator
- Glycoprotein Hormones, alpha Subunit
- Humans
- Methylation
