Article
Long-term (10-year) monitoring of transposon-mediated transgenic cattle.
Transgenic research - 1 Oct 2024
Yum Soo-Young, Choi Bae Young, Gim Gyeong-Min, Eom Kyeong-Hyeon, Lee Seong-Beom, Kim Daehyun, Lim Euntaek, Kim Do-Yoon, Heo Seong-Eun, Shim Donghwan, Jang Goo
Abstract excerpt
The production of transgenic animals using non-viral methods has raised questions regarding their long-term health and genomic stability. In this study, we evaluated these aspects in transgenic cattle over ten years, using transposon-mediated gene transfer. Our longitudinal analysis included a comprehensive health assessment and whole-genome DNA resequencing. We found no significant alterations in physiological...
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