Article
Sequencing two Tyr::CreERT2 transgenic mouse lines.
Pigment cell & melanoma research - 1 May 2020
Aktary Zackie, Corvelo Andre, Estrin Camille, Larue Lionel
Abstract excerpt
The Cre/loxP system is a powerful tool that has allowed the study of the effects of specific genes of interest in various biological settings. The Tyr::CreERT2 system allows for the targeted expression and activity of the Cre enzyme in the melanocyte lineage following treatment with tamoxifen, thus providing spatial and temporal control of the expression of specific target genes. Two independent transgenic mouse...
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