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Article

Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.

Molecular biology of the cell - 1 Jul 1999

Rivas M P, Kearns B G, Xie Z, Guo S, Sekar M C, Hosaka K, Kagiwada S, York J D, Bankaitis V A

Abstract excerpt

SacIp dysfunction results in bypass of the requirement for phosphatidylinositol transfer protein (Sec14p) function in yeast Golgi processes. This effect is accompanied by alterations in inositol phospholipid metabolism and inositol auxotrophy. Elucidation of how sac1 mutants effect "bypass Sec14p" will provide insights into Sec14p function in vivo. We now report that, in addition to a dramatic accumulation of...

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Identifiers

PMID: 10397762
DOI: 10.1091/mbc.10.7.2235
PMCID: PMC25439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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