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Article

Cell wall integrity MAPK pathway is essential for lipid homeostasis.

The Journal of biological chemistry - 5 Dec 2008

Nunez Lilia R, Jesch Stephen A, Gaspar Maria L, Almaguer Claudia, Villa-Garcia Manuel, Ruiz-Noriega Monica, Patton-Vogt Jana, Henry Susan A

Abstract excerpt

The highly conserved yeast cell wall integrity mitogen-activated protein kinase pathway regulates cellular responses to cell wall and membrane stress. We report that this pathway is activated and essential for viability under growth conditions that alter both the abundance and pattern of synthesis and turnover of membrane phospholipids, particularly phosphatidylinositol and phosphatidylcholine. Mutants defective...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18842580
DOI: 10.1074/jbc.M806391200
PMCID: PMC2590691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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