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Article

Mutation rates, spectra and hotspots in mismatch repair-deficient Caenorhabditis elegans.

Genetics - 1 May 2005

Denver Dee R, Feinberg Seth, Estes Suzanne, Thomas W Kelley, Lynch Michael

Abstract excerpt

Although it is clear that postreplicative DNA mismatch repair (MMR) plays a critical role in maintaining genomic stability in nearly all forms of life surveyed, much remains to be understood about the genome-wide impact of MMR on spontaneous mutation processes and the extent to which MMR-deficient mutation patterns vary among species. We analyzed spontaneous mutation processes across multiple genomic regions...

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Identifiers

PMID: 15716493
DOI: 10.1534/genetics.104.038521
PMCID: PMC1449714

Genes

MSH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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