Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis.

The Journal of clinical investigation - 1 Mar 2000

Reynolds J, Tam F W, Chandraker A, Smith J, Karkar A M, Cross J, Peach R, Sayegh M H, Pusey C D

Abstract excerpt

Experimental autoimmune glomerulonephritis (EAG), an animal model of Goodpasture's disease, can be induced in Wistar Kyoto (WKY) rats by a single injection of rat glomerular basement membrane (GBM) in adjuvant. EAG is characterized by circulating and deposited anti-GBM antibodies, accompanied by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abatacept
Share to B7-1 Antigen
Share to Basement Membrane

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD28 Antigens

Share to Fibrin

Share to Glomerulonephritis

Share to Immunoconjugates

Share to Rats, Inbred Strains

Source

Open in PubMed Open full text

Identifiers

PMID: 10712436
DOI: 10.1172/JCI6710
PMCID: PMC289170

Genes

CTLA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10712436-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis.PMID 10712436Read ↗

Proliferative autoimmune glomerulonephritis in rats: a model for autoimmune glomerulonephritis in humans.Semantic proximity Read ↗

Effect of Chronic Uremia on the Cell Surface Expression of B7 Family Costimulatory Molecules in an HLA-A2 Transgenic Mouse Model of Chronic Kidney Disease.Semantic proximity Read ↗

Glomerulonephritis: immunopathogenesis and immunotherapySemantic proximity Read ↗

T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis.Semantic proximity Read ↗

Pathogenesis of minimal change nephrotic syndrome: an immunological conceptSemantic proximity Read ↗

Genetic susceptibility to experimental autoimmune glomerulonephritis in the Wistar Kyoto rat.Semantic proximity Read ↗

Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells.Semantic proximity Read ↗

Characterization of the renal CD4+ T-cell response in experimental autoimmune glomerulonephritis.Semantic proximity Read ↗

Strain differences and the genetic basis of experimental autoimmune anti-glomerular basement membrane glomerulonephritis.Semantic proximity Read ↗

Intramolecular Epitope Spreading in Heymann NephritisSemantic proximity Read ↗

Treatment of Murine Lupus with CTLA4IgSemantic proximity Read ↗

Developing therapeutic ‘arrows’ with the precision of William TellSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.