Article
Criss-crossed interactions between the enhancer and the att sites of phage Mu during DNA transposition.
The EMBO journal - 1 Jul 1999
Jiang H, Yang J Y, Harshey R M
Abstract excerpt
A bipartite enhancer sequence (composed of the O1 and O2 operator sites) is essential for assembly of the functional tetramer of phage Mu transposase (MuA) on supercoiled DNA substrates. A three-site interaction (LER) between the left (L) and right (R) ends of Mu (att sites) and the enhancer (E) precedes tetramer assembly. We have dissected the role of the enhancer in tetramer assembly by using two transposase...
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