Article
Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.
Nature genetics - 1 Jul 1999
McPherron A C, Lawler A M, Lee S J
Abstract excerpt
The bones that comprise the axial skeleton have distinct morphological features characteristic of their positions along the anterior/posterior axis. We previously described a novel TGF-beta family member, myostatin (encoded by the gene Mstn, formerly Gdf8), that has an essential role in regulating skeletal muscle mass. We also identified a gene related to Mstn by low-stringency screening. While the work described...
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