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Article

P‐Glycoprotein, Multidrug Resistance and Protein Kinase C

1 Jan 1996

Abstract excerpt

The multidrug resistant (MDR) phenotype is a well-studied subject that has been recognized as a determinant underlying specific types of drug resistance in human cancer. Although it is clear that the P-glycoprotein plays a major role in MDR, it is not clear whether post-translational modifications such as phosphorylation have any major impact on its modulation. The laboratory of Dr. Bruce Chabner was one of the...

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PMID: 10388000
DOI: 10.1002/stem.140047

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