Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Nef protein of primate lentiviruses

1 Apr 1999

Abstract excerpt

The Nef protein of primate lentiviruses acts as an important virulence factor in vivo both in monkeys and in humans. Among a human cohort of long-term non-progressors, several Nef defective HIV1 viruses have been isolated, indicating that Nef may accelerate HIV progression and disease in humans. Additionally, a Nef-deleted SIV virus has low titres in rhesus monkeys and the animals develop AIDS at a much slower...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10386338
DOI: 10.1002/(sici)1099-1654(199904/06)9:2<111::aid-rmv245>3.0.co;2-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Nef protein of primate lentivirusesPMID 10386338Read ↗

The activity of Nef on HIV-1 infectivitySemantic proximity Read ↗

Role of Nef in primate lentiviral immunopathogenesisSemantic proximity Read ↗

Interactions of HIV-1 NEF with cellular signal transducing proteinsSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Nef: Adapting to Intracellular Trafficking PathwaysSemantic proximity Read ↗

The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection.Semantic proximity Read ↗

In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesisSemantic proximity Read ↗

HIV ‐1 Nef: Taking Control of Protein TraffickingSemantic proximity Read ↗

Primate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene ExpressionSemantic proximity Read ↗

Molecular and mechanistic analysis of HIV NefSemantic proximity Read ↗

Functional association between the nef gene product and gag-pol region of HIV-1.Semantic proximity Read ↗

How HIV Nef Proteins Hijack Membrane Traffic To Promote InfectionSemantic proximity Read ↗

The paradox of HIV nef function: resolution of the contradictions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.