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Article

The activity of Nef on HIV-1 infectivity

20 May 2014

Abstract excerpt

The replication and pathogenicity of lentiviruses is crucially modulated by "auxiliary proteins" which are expressed in addition to the canonical retroviral ORFs gag, pol, and env. Strategies to inhibit the activity of such proteins are often sought and proposed as possible additions to increase efficacy of the traditional antiretroviral therapy. This requires the acquisition of an in-depth knowledge of the...

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Identifiers

PMID: 24904546
DOI: 10.3389/fmicb.2014.00232

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