Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosomal influence on meiotic spindle assembly: abnormal meiosis I in female Mlh1 mutant mice.

The Journal of cell biology - 28 Jun 1999

Woods L M, Hodges C A, Baart E, Baker S M, Liskay M, Hunt P A

Abstract excerpt

In mouse oocytes, the first meiotic spindle is formed through the action of multiple microtubule organizing centers rather than a pair of centrosomes. Although the chromosomes are thought to play a major role in organizing the meiotic spindle, it remains unclear how a stable bipolar spindle is established. We have studied the formation of the first meiotic spindle in murine oocytes from mice homozygous for a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphase
Share to Centrosome
Share to Chromosome Segregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kinetochores

Share to Meiosis

Share to MutL Protein Homolog 1

Share to Sex Chromosomes

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 10385520
DOI: 10.1083/jcb.145.7.1395
PMCID: PMC2133173

Genes

MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosomal influence on meiotic spindle assembly: abnormal meiosis I in female Mlh1 mutant mice.PMID 10385520Read ↗

Meiotic prophase abnormalities and metaphase cell death in MLH1-deficient mouse spermatocytes: insights into regulation of spermatogenic progress.Semantic proximity Read ↗

Kinetochore microtubule establishment is defective in oocytes from aged miceSemantic proximity Read ↗

Changing Mad2 Levels Affects Chromosome Segregation and Spindle Assembly Checkpoint Control in Female Mouse Meiosis ISemantic proximity Read ↗

Merotelic kinetochore attachment in oocyte meiosis II causes sister chromatids segregation errors in aged miceSemantic proximity Read ↗

Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes.Semantic proximity Read ↗

The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice.Semantic proximity Read ↗

Mlh1 deficiency in zebrafish results in male sterility and aneuploid as well as triploid progeny in females.Semantic proximity Read ↗

Meiotic Pachytene Arrest in MLH1-Deficient MiceSemantic proximity Read ↗

The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male miceSemantic proximity Read ↗

Lack of Checkpoint Control at the Metaphase/Anaphase Transition: A Mechanism of Meiotic Nondisjunction in Mammalian FemalesSemantic proximity Read ↗

Aurora kinase B modulates chromosome alignment in mouse oocytesSemantic proximity Read ↗

Completion of meiosis in male zebrafish (Danio rerio) despite lack of DNA mismatch repair gene mlh1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.