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Article

Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro.

Infection and immunity - 1 Jan 2004

Sanchez Angela A, Johnston Douglas A, Myers Carter, Edwards John E, Mitchell Aaron P, Filler Scott G

Abstract excerpt

Candida albicans must penetrate the endothelial cell lining of the vasculature to invade the deep tissues during a hematogenously disseminated infection. We compared 27 C. albicans mutants with their wild-type parent for their capacity to damage endothelial cells in vitro and cause a lethal infection in mice following tail vein inoculation. Of 10 mutants with significantly impaired capacity to damage endothelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14688143
DOI: 10.1128/IAI.72.1.598-601.2004
PMCID: PMC344013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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