Article
Chromosomal rearrangements associated with morphological mutants provide a means for genetic variation of Candida albicans.
Journal of bacteriology - 1 Mar 1990
Rustchenko-Bulgac E P, Sherman F, Hicks J B
Abstract excerpt
At frequencies as high as 1.4%, the pathogenic yeast Candida albicans spontaneously gave rise to morphological mutants exhibiting more than 20 different types of abnormal colonies; approximately two-thirds of the mutants were stable, while the other one-third were unstable and produced mixtures of different colonial forms at very high rates. Abnormal electrophoretic karyotypes were observed for all of the 14...
Topics
- Candida albicans
- Chromosomes, Fungal
- DNA, Fungal
- Electrophoresis
- Genetic Variation
- Karyotyping
- Mutation
- Nucleic Acid Hybridization