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Article

Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations.

Genomics - 15 Jun 1999

Marsh S, Collie-Duguid E S, Li T, Liu X, McLeod H L

Abstract excerpt

Thymidylate synthase (TS) regulates the production of DNA synthesis precursors and is an important target of cancer chemotherapy. A tandem repeat sequence in a TS promoter enhancer region (TSER) was recently identified. Polymorphic variation affected in vitro expression levels of the gene. We eva...

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Identifiers

PMID: 10373329
DOI: 10.1006/geno.1999.5833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10373329-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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