Article
Heterozygote deficiency in thymidylate synthase enhancer region polymorphism genotype distribution in Hungarian colorectal cancer patients.
International journal of cancer - 1 Mar 2004
Adleff Vilmos, Hitre Erika, Köves István, Orosz Zsolt, Hajnal Anna, Kralovánszky Judit
Abstract excerpt
Thymidylate synthase (TS) gene polymorphisms are important as prognostic factors in cancer chemotherapy, but recent results describe that the TS enhancer region (TSER) polymorphic genotypes may also modulate risk for malignancies. Two functionally important and ethnically diverse polymorphisms ar...
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