Article
Thymidylate synthase enhancer region: Novel allele in Indians.
Annals of human biology - 1 Feb 2017
Dhawan Dipali, Padh Harish
Abstract excerpt
BACKGROUND: Thymidylate synthase (TS) is the major target for fluoropyrimidine drugs like 5-Fluorouracil (5-FU). There are polymorphic tandem repeats in the TYMS gene enhancer region (TSER). The number of tandem repeats varies in different populations. The aim of this study was to determine the frequencies of the TSER tandem repeats (rs34743033) and compare the observed frequencies with those of other...
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