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Article

Genetic variants in the enhancer region of the thymidylate synthase gene in the Chilean population.

British journal of clinical pharmacology - 1 Jun 2006

Acuña M, Eaton L, Cifuentes L, Massardo D

Abstract excerpt

AIMS: Thymidylate synthase (TYMS) is an important target enzyme for the fluoropyrimidines. The TYMS gene enhancer region possesses tandemly repeated (TSER) sequences that are polymorphic in humans and different among ethnic groups. The aims of this study were to estimate the frequencies of the TSER variants in two hospital samples located in the northern (HSJ) and eastern (CLC) parts of Santiago, Chile, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16722845
DOI: 10.1111/j.1365-2125.2006.02595.x
PMCID: PMC1885121

Genes

CLC
TYMS

Provenance

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