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Article

Derivation and characterization of replicate high- and low-alcohol preferring lines of mice and a high-drinking crossed HAP line.

Behavior genetics - 1 Mar 2011

Oberlin Brandon, Best Christina, Matson Liana, Henderson Angela, Grahame Nicholas

Abstract excerpt

Selectively breeding lines of mice and rats to differ in alcohol intake has proven useful for defining which traits correlate with high alcohol drinking behavior, as well as for creating animal models of alcoholism. This study reports the derivation of two novel sets of selected lines, High Alcohol Preferring (HAP) and Low Alcohol Preferring (LAP) replicate 2 and 3 lines. Mice were mass-selected using the same...

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Identifiers

PMID: 20853157
DOI: 10.1007/s10519-010-9394-5
PMCID: PMC4041157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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