Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Response to selection for ethanol-induced locomotor activation: genetic analyses and selection response characterization.

Psychopharmacology - 1 Jan 1991

Phillips T J, Burkhart-Kasch S, Terdal E S, Crabbe J C

Abstract excerpt

Selectively bred FAST mice are highly susceptible, while SLOW mice are less susceptible, to the locomotor stimulant effects of ethanol. Heritability estimates indicate that approximately 15% of the variance in the FAST lines is of additive genetic origin, while low susceptibility is ostensibly nonheritable. Inbreeding has increased at the rate of 2% per generation, but fertility has been unaffected. Measurement...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dose-Response Relationship, Drug
Share to Ethanol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Injections, Intravenous

Share to Motor Activity

Share to Phenotype

Source

Identifiers

PMID: 2062990
DOI: 10.1007/BF02244259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Response to selection for ethanol-induced locomotor activation: genetic analyses and selection response characterization.PMID 2062990Read ↗

Bidirectional selective breeding for ethanol effects on locomotor activity: characterization of FAST and SLOW mice through selection generation 35.Semantic proximity Read ↗

Ethanol self-administration is genetically independent of locomotor stimulation in fast and slow mice.Semantic proximity Read ↗

Seizure sensitivity and GABAergic modulation of ethanol sensitivity in selectively bred FAST and SLOW mouse lines.Semantic proximity Read ↗

Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes.Semantic proximity Read ↗

Selective breeding for high and low alcohol preference in mice.Semantic proximity Read ↗

Ethanol-induced activation and rapid development of tolerance may have some underlying genes in common.Semantic proximity Read ↗

Response to selection for sensitivity to ethanol hypothermia: genetic analyses.Semantic proximity Read ↗

Accentuating effects of nicotine on ethanol response in mice with high genetic predisposition to ethanol-induced locomotor stimulation.Semantic proximity Read ↗

Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity.Semantic proximity Read ↗

Genetic-environment analysis of sensitivity and acute tolerance to ethanol in mice.Semantic proximity Read ↗

Quantitative trait loci contributing to physiological and behavioural ethanol responses after acute and chronic treatment.Semantic proximity Read ↗

Selective breeding for initial sensitivity to ethanol.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.