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Article

Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice.

Human molecular genetics - 1 Jul 1999

Cutts S M, Fowler K J, Kile B T, Hii L L, O'Dowd R A, Hudson D F, Saffery R, Kalitsis P, Earle E, Choo K H

Abstract excerpt

INCENP is a chromosomal passenger protein which relocates from the centromere to thel spindle midzone during the metaphase-anaphase transition, ultimately being discarded in the cell midbody at the completion of cytokinesis. Using homologous recombination, we have generated Incenp gene-targeted heterozygous mice that are phenotypically indistinguishable from their wild-type littermates. Intercrossing the...

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Identifiers

PMID: 10369859
DOI: 10.1093/hmg/8.7.1145

Genes

INCENP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice.PMID 10369859Read ↗

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