Article
Mapping genes for common diseases: the case for genetic (LD) maps.
Human heredity - 1 Jan 2004
Collins Andrew, Lau Winston, De La Vega Francisco M
Abstract excerpt
We examine the current effort to develop a haplotype map of the human genome and suggest an alternative approach which represents linkage disequilibrium patterns in the form of a metric LD map. LD maps have some of the useful properties of genetic linkage maps but have a much higher resolution which is optimal for SNP-based association mapping of common diseases. The studies that have been undertaken to date...
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