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Article

CA repeat allele polymorphism in the first intron of the human interferon-gamma gene is associated with lung allograft fibrosis.

Human immunology - 1 Apr 1999

Awad M, Pravica V, Perrey C, El Gamel A, Yonan N, Sinnott P J, Hutchinson I V

Abstract excerpt

Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. In this study we have analysed the association between genetically-determined high IFN-gamma production and development of fibrosis in lung transplants. The human IFN-gamma gene has a variable length CA repeat in the first intron. Our previous study showed that polymorphism of this...

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Identifiers

PMID: 10363726
DOI: 10.1016/s0198-8859(98)00133-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CA repeat allele polymorphism in the first intron of the human interferon-gamma gene is associated with lung allograft fibrosis.PMID 10363726Read ↗

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