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Interleukin-6 and interferon-?? gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantation1

1 Nov 2002

Abstract excerpt

BACKGROUND: A number of genetic polymorphisms have been shown to regulate the production and secretion of tumor necrosis factor (TNF)-alpha, transforming growth factor (TGF)-beta1, interferon (IFN)-gamma, interleukin (IL)-6, and IL-10. Several of these genetic polymorphisms have been shown to be associated with either acute or chronic rejection of kidney, liver, and heart allografts and with development of...

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PMID: 12451269
DOI: 10.1097/00007890-200211150-00017

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