Article
Recipient gene polymorphisms in the Th-1 cytokines IL-2 and IFN-gamma in relation to acute rejection and graft vascular disease after clinical heart transplantation.
Transplant immunology - 1 Jan 2000
Holweg C T J, Peeters A M A, Balk A H M M, Uitterlinden A G, Niesters H G M, Maat A P W M, Weimar W, Baan C C
Abstract excerpt
IL-2 and IFN-gamma are associated with acute rejection (AR) and graft vascular disease (GVD) after clinical heart transplantation. Polymorphisms in the genes of IL-2 (T-330G in the promoter) and IFN-gamma (CA repeat in the first intron) influence the production levels of these cytokines. Therefore, these polymorphisms might have an effect on the outcome after transplantation. To investigate possible effects of...
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