Article
Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation.
Transplantation - 15 Mar 2001
Asderakis A, Sankaran D, Dyer P, Johnson R W, Pravica V, Sinnott P J, Roberts I, Hutchinson I V
Abstract excerpt
BACKGROUND: Our group has previously described five different size alleles of an interferon (IFN)-gamma microsatellite. Analyzing this polymorphism, this study correlated high IFN-gamma production with a 12 CA repeat allele (allele 2). Further, our group has described interleukin (IL)-10 polymorphism defining in vitro high and low IL-10 producer status. METHODS: Samples from 88 of 115 consecutive cadaveric renal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.