In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene.

doi:10.1046/j.1365-2370.1999.00122.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Feb 1999

Pravica V, Asderakis A, Perrey C, Hajeer A, Sinnott P J, Hutchinson I V

Abstract excerpt

The DNA sequence of the human IFN-gamma gene shows the presence of a variable-length CA repeat in the first intron of the gene. We investigated the allele distribution of this microsatellite region in 164 unrelated healthy individuals, and the association with interferon-gamma (IFN-gamma) production. In vitro production of IFN-gamma showed a significant correlation with the presence of allele #2.

Topics

Alleles
Chromosomes, Human, Pair 12
Dinucleotide Repeats
Enzyme-Linked Immunosorbent Assay
Genetic Testing
Genotype
Humans
Interferon-gamma
Molecular Sequence Data
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 10068907
DOI: 10.1046/j.1365-2370.1999.00122.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics