Article
Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity.
Genetics - 1 Jan 2008
Yamawaki Tracy M, Arantes-Oliveira Nuno, Berman Jennifer R, Zhang Peichuan, Kenyon Cynthia
Abstract excerpt
The two parts of the Caenorhabditis elegans reproductive system, the germ cells and the somatic reproductive tissues, each influence the life span of the animal. Removing the germ cells increases longevity, and this life span extension requires the somatic gonad. Here we show that the somatic gonad and the germ cells make distinct contributions to life span determination. The life span increase produced by loss...
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