Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila.

The Journal of cell biology - 9 Aug 1999

Robinson J T, Wojcik E J, Sanders M A, McGrail M, Hays T S

Abstract excerpt

Cytoplasmic dynein is a multisubunit minus-end-directed microtubule motor that serves multiple cellular functions. Genetic studies in Drosophila and mouse have demonstrated that dynein function is essential in metazoan organisms. However, whether the essential function of dynein reflects a mitotic requirement, and what specific mitotic tasks require dynein remains controversial. Drosophila is an excellent genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrosome
Share to Dyneins
Share to Giant Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interphase

Share to Microtubules

Share to Movement

Share to Nuclear Envelope

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 10444068
DOI: 10.1083/jcb.146.3.597
PMCID: PMC2150560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila.PMID 10444068Read ↗

The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila.Semantic proximity Read ↗

Drosophila cytoplasmic dynein, a microtubule motor that is asymmetrically localized in the oocyte.Semantic proximity Read ↗

Cytoplasmic dynein function is essential in Drosophila melanogaster.Semantic proximity Read ↗

Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations.Semantic proximity Read ↗

Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.Semantic proximity Read ↗

Mutations in centrosomin reveal requirements for centrosomal function during early Drosophila embryogenesis.Semantic proximity Read ↗

Review: Cytoplasmic dynein motors in photoreceptors.Semantic proximity Read ↗

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.Semantic proximity Read ↗

Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development.Semantic proximity Read ↗

Genetic analysis of dynein function in the nervous system and in mitosisSemantic proximity Read ↗

Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation.Semantic proximity Read ↗

Mechanism of positioning the cell nucleus in vertebrate photoreceptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.