Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent.

The Journal of cell biology - 13 May 2002

Hannak Eva, Oegema Karen, Kirkham Matthew, Gönczy Pierre, Habermann Bianca, Hyman Anthony A

Abstract excerpt

gamma-Tubulin-containing complexes are thought to nucleate and anchor centrosomal microtubules (MTs). Surprisingly, a recent study (Strome, S., J. Powers, M. Dunn, K. Reese, C.J. Malone, J. White, G. Seydoux, and W. Saxton. Mol. Biol. Cell. 12:1751-1764) showed that centrosomal asters form in Caenorhabditis elegans embryos depleted of gamma-tubulin by RNA-mediated interference (RNAi). Here, we investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrosome
Share to Dyneins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helminth Proteins

Share to Microtubule-Associated Proteins

Share to Microtubules

Share to Mitosis

Share to Spindle Apparatus

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 12011109
DOI: 10.1083/jcb.200202047
PMCID: PMC2173857

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent.PMID 12011109Read ↗

Drosophila melanogaster gamma-TuRC is dispensable for targeting gamma-tubulin to the centrosome and microtubule nucleation.Semantic proximity Read ↗

Polarization of the anterior-posterior axis of C. elegans is a microtubule-directed process.Semantic proximity Read ↗

The role of γ-tubulin in centrosomal microtubule organization.Semantic proximity Read ↗

A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization.Semantic proximity Read ↗

Drosophila Wee1 interacts with members of the gammaTURC and is required for proper mitotic-spindle morphogenesis and positioning.Semantic proximity Read ↗

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.Semantic proximity Read ↗

The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in the <i>C. elegans</i> germ lineSemantic proximity Read ↗

Dominant-negative mutant dynein allows spontaneous centrosome assembly, uncouples chromosome and centrosome cycles.Semantic proximity Read ↗

Overexpression of truncated gamma-tubulins disrupts mitotic aster formation in Xenopus oocyte extracts.Semantic proximity Read ↗

Maternal regulation of the vertebrate egg-to-embryo transitionSemantic proximity Read ↗

The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline.Semantic proximity Read ↗

Microtubule stiffening by the doublecortin-domain protein ZYG-8 contributes to mitotic spindle orientation during zygote division in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.