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Dominant-negative mutant dynein allows spontaneous centrosome assembly, uncouples chromosome and centrosome cycles.

Current biology : CB - 23 Jan 2001

Belecz I, Gonzalez C, Puro J, Szabad J

Abstract excerpt

Cleavage cycles commence and chromosome and centrosome cycles proceed in harmony following fertilization of Drosophila eggs and completion of the meiotic divisions. The sperm-introduced centrioles replicate, separate, and while recruit pericentriolar material centrosomes (CS) form. The CS nucleate asters of microtubules (MT). Spindles form following interaction of some astral MT with kinetochores. In unfertilized...

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PMID: 11231132
DOI: 10.1016/s0960-9822(01)00025-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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