Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of Recombination between Diverged Sequences in Wild-Type and BLM-Deficient Mouse and Human Cells

12 Feb 2010

Abstract excerpt

Double-strand breaks (DSBs) are particularly deleterious DNA lesions for which cells have developed multiple mechanisms of repair. One major mechanism of DSB repair in mammalian cells is homologous recombination (HR), whereby a homologous donor sequence is used as a template for repair. For this reason, HR repair of DSBs is also being exploited for gene modification in possible therapeutic approaches. HR is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to DNA Repair Mechanisms
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20154148
DOI: 10.1128/mcb.01553-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of Recombination between Diverged Sequences in Wild-Type and BLM-Deficient Mouse and Human CellsPMID 20154148Read ↗

Homologous and homeologous intermolecular gene conversion are not differentially affected by mutations in the DNA damage or the mismatch repair genes RAD1, RAD50, RAD51, RAD52, RAD54, PMS1 and MSH2.Semantic proximity Read ↗

Double-Strand Break Repair by Interchromosomal Recombination: An In Vivo Repair Mechanism Utilized by Multiple Somatic Tissues in MammalsSemantic proximity Read ↗

Induction of recombination between homologous and diverged DNAs by double-strand gaps and breaks and role of mismatch repair.Semantic proximity Read ↗

Homologous Recombination Subpathways: A Tangle to ResolveSemantic proximity Read ↗

Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange.Semantic proximity Read ↗

Analysis of DNA double-strand break repair pathways in mice.Semantic proximity Read ↗

Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells.Semantic proximity Read ↗

Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae.Semantic proximity Read ↗

Gene conversion tracts in Saccharomyces cerevisiae can be extremely short and highly directional.Semantic proximity Read ↗

Mitotic Crossovers between Diverged Sequences Are Regulated by Mismatch Repair Proteins in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cellsSemantic proximity Read ↗

Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.