Article
Regulation of mRNA splicing and transport by the tyrosine kinase activity of src.
Oncogene - 22 Apr 1999
Gondran P, Dautry F
Abstract excerpt
The regulation of transcription by signal transduction pathways is well documented. In addition, we have previously shown that src can regulate pre-mRNA processing. To investigate which functional domains of src are involved in the regulation of splicing and transport of Lymphotoxin alpha (LTalpha) transcripts, we have used src mutants in the catalytic, SH2 and SH3 domains in association with the Y527F or the...
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