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Article

Molecular Characterization and Human T-Cell Responses to a Member of a Novel<i>Mycobacterium tuberculosis mtb39</i>Gene Family

1 Jun 1999

Abstract excerpt

We have used expression screening of a genomic Mycobacterium tuberculosis library with tuberculosis (TB) patient sera to identify novel genes that may be used diagnostically or in the development of a TB vaccine. Using this strategy, we have cloned a novel gene, termed mtb39a, that encodes a 39-kDa protein. Molecular characterization revealed that mtb39a is a member of a family of three highly related genes that...

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PMID: 10338503
DOI: 10.1128/iai.67.6.2941-2950.1999

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