Article
Immunological Characterization of Antigens Encoded by the RD1 Region of the <i>Mycobacterium tuberculosis</i> Genome
1 Nov 2001
Abstract excerpt
Development of immunoassays specific for the diagnosis of tuberculosis requires antigens unique to Mycobacterium tuberculosis. In a search for such antigens we tested six proteins encoded by RD1, a region present in M. tuberculosis and virulent M. bovis genomes but missing from the DNA of all substrains of M. bovis Bacillus Calmette-Guerin (BCG). The six proteins (Rv3871, Rv3872, Rv3873, MTSA-10, ESAT-6 and...
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